Description

1. 1. Relevant identified uses of the substance or mixture and uses advised against

      1. Relevant identified uses OF

         Titanium Doixide for sale

         As colouring and opacifying agent in the following industries: Coatings and Paints

         Printing Plastics Synthetic Fibres Paper

         Rubber Ceramics Cement Cosmetics

         1.12) Uses advised against

         None

2. Composition  Of

   Titanium Doixide for sale

   Hazardous ingredients Titanium dioxide, TiO₂

   Typical composition (%) >82

   CAS Number 13463-67-7

   EINECS/EC Label Number 236-675-5

3. Hazard Identification

   1. Classification of the substance or mixture

Classification according to Regulation (EC) No. 1272/2008 [CLP]

Titanium dioxide according to Regulation (EC) No. 1273/2008 is not classified as dangerous.

Classification according to Directive 67/548/EEC

Titanium dioxide according to Directive (EC) No. 67/548/EEC is not classified as dangerous.

Human health effects

Skin effect: Skin is not penetrated, but prolonged contact can cause irritation. Eyes effect: Feeling of a strange body in the eyes.

Swallowing: No hazard during normal industrial use.

Inhalation: Chemically neutral dust. Excessive exposure may cause temporary drying effect and/or irritation of mucous membranes

1. 1. Label Elements

      Labelling according to Regulation (EC) No. 1272/2008 (CLP)

      No labelling required according to Regulation (EC) No. 1272/2008

   2. Other Hazards

Titanium dioxide is neither a PBT or a vPvB substance.

1. First Aid Measures

   1. Description of First Aid Measures

      Ingestion: No adverse health effects anticipated by this route.

      Inhalation: Move to a fresh air atmosphere. In case of persistent symptoms, consult a doctor.

      Skin: Remove contaminated clothing, and wash affected areas thoroughly with soap and water. If skin irritation or rash occurs: Get medical advice/attention. Show label if possible.

      Eyes: Irrigate eyeball thoroughly with water for at least 10 minutes. If discomfort persists seek medical attention.

   2. Most important symptoms and effects, both acute and delayed

      Acute and delayed symptoms and effects do not occur in normal conditions of use

   3. Indication of any immediate medical attention and special treatment needed

      No special requirements. Medical assistance may be required if large amounts of dust are inhaled.

2. Fire Fighting

   1. Extinguishing media

      Suitable extinguishing media Any type to be selected according to materials stored

      in the immediate neighbourhood.

      Unsuitable extinguishing media None.

   2. Special hazards arising from the substance or mixture

      Non-flammable. Extinguish surrounding fires with appropriate methods.

   3. Advice for firefighters

      Protection during firefighting: Use of approved supplied air or self-contained

      breathing apparatus operated in positive pressure mode are satisfactory. Totally impervious protective suits, gloves, and boots must be worn

3. Accidental Release Measures

   1. Personal precautions, protective equipment and emergency procedures

      General measures: Keep public away from danger area. See section 8.2. Avoid dust production. Avoid all contact with this substance.

      1. For non-emergency personnel

         No additional information available

      2. For emergency responders

         No additional information available

   2. Environmental precautions

      Prevent entry to sewers and soil. Notify authorities if product enters sewers or public waters.

   3. Methods and material for containment and cleaning up

      Methods for cleaning up: Collect mechanically and transfer into appropriate container for disposal. Avoid dust production.

   4. Reference to other sections

      See section 8 and 13 for more information.

4. Handling/Storage

   1. Precautions for safe handling

      Precautions for safe handling: Do not breathe dust.

      Avoid all contact with this substance.

      Wash hands plentifully and other exposed areas with water after handling.

      Remove contaminated clothing and shoes. Wash clothing before reusing.

      Packagings: Even those that have been emptied will retain product residue. Always obey safety warnings and handle empty packagings as if they were full.

      Avoid all contact with this substance.

      Hygiene measures: When using do not eat, drink or smoke. Wash hands and other exposed areas with mild soap and water before eat, drink or smoke and when leaving work. Remove contaminated clothing and shoes.

      7.2. Conditions for safe storage, including any incompatibilities

      Storage conditions: Store in dry, cool, well-ventilated area. Keep away from food, drink and animal feeding stuffs.

      Incompatible products: None known

      7.3. Specific end use(s)

      No additional information available

5. Exposure Controls and Personal Protection

   1. Exposure Limits

      WEL long term exposure limit (8-hour TWA reference period) 10mg/m3 (total inhalable)

      4mg/m3 (respirable)

      DNEL’s for workers

      Long term – local effects . Inhalation. 10mg/m3

      DNEL’s for the general population

      Long term – systemic effects . Oral. 700mg/m3 bw/day

      PNEC’s

      End Use Value

      Aqua (freshwater) 0.127mg/L Aqua (Intermittent release) 0.61mg/L Aqua (marine water) 1 mg/L

      Sediment (freshwater) 1,000 mg/L Sediment (marine water) 100 mg/L

      Soil 0.000733mg/kg

      STP 100mg/L

   2. Occupational Exposure controls

      Appropriate engineering controls: Use as far as possible in a closed system. Provide a

      regular control of the atmosphere. Emergency eye wash fountains and safety showers should be available in the immediate vicinity of any potential exposure.

      Local exhaust and general ventilation must be adequate to meet exposure standards. Please refer to the annex (exposure scenarios).

      Hand protection: Use gloves resistant to chemical products

      corresponding to EN 374:3. Take advice to gloves’ supplier.

      Eye protection: Wear safety glasses with side shields according EN 166.

      Skin and body protection: Wear closed protective clothing.

      Respiratory protection: Use respiratory protection mask according to EN 140

      or EN 405 with filter type P3 according to EN 143:2000 or FFP3 according to EN 149:2001.

      Environmental exposure controls: Prevent entry to sewers and soil.

6. Physical/Chemical Properties of

   Titanium Doixide for sale

   Physical state Solid crystalline powder

   Colour white

   Odour odourless

   Odour threshold Not applicable

   pH 6 – 8

   Relative evaporation rate (butylacetate=1) No data available Melting point 1,843 °C

   Freezing point No data available

   Boiling point (at 1,1013 hPa) Ca. 3,0000 C

   Flash point Not flammable

   Decomposition temperature No data available

   Flammability (solid, gas) Not flammable

   Vapour pressure Not applicable

   Density at 200C 4.26 kg/L

   Solubility in water 1 µg/L at pH 6, 7 and 8

   Bulk Density 800 – 1,300 kg/m3

   Viscosity, kinematic Not applicable

   Viscosity, dynamic No data available

   Explosive properties No data available

   Oxidising properties Non-oxidising

   Explosive limits Not applicable

   1. Other information

      Molecular formula: TiO2

7. Stability/Reactivity

   1. Reactivity

      Stable under normal conditions of handling and storage.

   2. Chemical stability

      Stable under normal conditions of handling and storage.

   3. Possibility of hazardous reactions

      Stable under normal conditions of handling and storage.

   4. Conditions to avoid

      Protect from moisture

   5. Incompatible materials

      None

   6. Hazardous decomposition products

      No information available

8. Toxicological Info OF Titanium Doixide for sale

   1. Information on toxicological effects Acute Toxicity

      Oral: LD50 rat >5,000mg/kg bw (OECD 425)

      Dermal: LD50 rabbit >5,000mg/kg bw Inhalative: LC50 rat >6.8mg/l (4h)

      Corrosivity/Irritation

      Respiratory Tract: Not irritating Skin: Not irritating (OECD 404) Eyes: Not irritating (OECD 405)

      Sensitization

      Not sensitizing (OECD 406, OECD 429)

      Repeated dose

      NOAEL: ORAL. 3,500mg/kg bw/day (chronic rat)

      Toxicity

      NOAEC: INHALATION. (Target organ – respiratory lung) 10mg/m3 (chronic rat)

      Toxicity for reproduction

      Based on the weight of evidence from the available long-term toxicity/carcinogenicity studies in rodents and the relevant information on the toxicokinetic behaviour in rats it is concluded that Titanium dioxide does not present a reproductive toxicity hazard.

9. Ecological Information

   1. Toxicity of Titanium Dioxide for sale in USA

      Titanium dioxide does not fulfil the toxic criteria.

      Aquatic compartment (including sediment)

      Short-term toxicity to fish LC50 for freshwater fish 1,000mg/L

      LC50 for marine water fish 10,000mg/L

      Long-term toxicity to fish No reliable chronic toxicity data

      are available for fish and the requirement for new test results is waived

      Short-term toxicity to EC50/LC50 for freshwater 1,000mg/L aquatic invertebrates invertebrates

      EC50/LC50 for marine water 10,000mg/L invertebrates

      Long-term toxicity to No reliable chronic toxicity aquatic invertebrates data are available for aquatic

      invertebrates and the requirement for new test results is waived

      Algae and aquatic plants EC50/LC50 for freshwater algae 61mg/L

      (Pseudokirchgneriella subcapitata)

      EC50/LC50 for marine water algae 10,000mg/L

      (Skeletonema costatum)

      EC10/LC10 or NOEC for 12.7mg/L freshwater algae

      EC10/LC10 or NOEC for Marine 5,600mg/L water algae

      Toxicity to aquatic EC50/LC50 for aquatic 1,000mg/L micro-organisms micro-organisms

      EC50/LC50 or NOEC for aquatic 1,000mg/L micro-organisms

      Sediment organisms EC50/LC50 for freshwater sediment 100,000mg/kg sediment

      dw (Hyalella azteca) EC50/LC50 for marine water 14,989 mg/kg sediment sediment dw (amphipod volutator

      Corophium) EC10/LC10 or NOEC for 100,000 mgkg sediment freshwater sediment dw

      Terrestrial compartment

      Toxicity to terrestrial arthropods	Long term EC10/LC10 pr NOEC for soil arthropods	1,000mg/kg soil dw
      Toxicity to terrestrial plants	Long term EC10/LC10 pr NOEC for terrestrial plants	100,000mg/kg soil dw
      Toxicity to soil micro-organisms	Long term EC10/LC10 pr NOEC micro-organisms	10,000mg/kg soil dw

      1. 1. Persistence and degradability

            Titanium dioxide does not fulfil the PBT or vPvB criteria.

         2. Bioaccumulative potential

            Titanium dioxide does not fulfil the PBT or vPvB criteria.

         3. Mobility in soil

            Titanium dioxide pigments have very limited mobility, since they are insoluble in water and other solvents.

         4. Results of PBT and vPvB assessment

            Not classified as PBT or vPvB.

         5. Other adverse effects

      None anticipated

10. Disposal Consideration

    1. 1. Waste treatment methods

          Recover or recycle if possible. Dispose of contents in accordance with local, national or international legislation

       2. Additional Information

    No information available

11. Transport Information

    In accordance with ADR / RID / ADNR / IMDG / ICAO / IATA

    1. 1. UN number

          Not applicable

       2. UN proper shipping name

          Not classified as dangerous according to Transport Regulations

       3. Transport hazard class(es)

          Not applicable

       4. Packing group

          Not applicable

       5. Environmental hazards Titanium Oxide for sale

          Other information: No supplementary information available.

       6. Special precautions for user

          1. Overland transport

             Not applicable

          2. Transport by sea

             No additional information available

          3. Air transport

             No additional information available

       7. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

    Not applicable

12. Regulatory Information

    1. 1. Safety, health and environmental regulations/legislation specific for the substance or mixture

          EU Legislation:

          Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18th December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulations (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC, including amendments. Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16th December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 with amendments.

       2. Chemical Safety Assessment

    A chemical safety assessment has been carried out.

13. Other Information

16.1. Indications of change

1. Original Document
2. Formatting Changes

International Agency for Research on cancer (IARC) has classified titanium dioxide in to Group 2B “Possibly carcinogenic to humans”. This classification is based on the IARC rules which state: there is “Sufficient evidence of carcinogenicity:….if…..two or more

independent studies in one species of animals carried out at different laboratories or under different protocols” show evidence of tumors. The IARC expert group judged three studies on rats as qualifying.

However there is no evidence that titanium dioxide itself has toxic properties that would lead to cancer, nor that it presents a carcinogenic risk to humans at exposures experienced in the workplace.

Training

Employees should be trained in the scope of proper substance handling. Read the safety data sheet before use.

The following Acronyms may be found in this document LD50:

DNEL: Derived No Effect Level

LTEL: Long Term Exposure Limit

NIOSH: National Institute of Occupational Safety and Health OEL: Occupational Exposure Limits

OSHA: Occupational Safety and Health Administration

PBT: Persistent, Bioaccumulative and Toxic

PNEC: Predicted No Effect Concentration

STEL: Short Term Exposure Limit

STOT: Specific Target Organ Toxicity

TLV – TWA: Threshold Limit Value – Time Weighted Average vPvB: Very persistent and very Bioaccumulative

WEL: Workplace Exposure Limit (UK HSE EH40)

This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product.

DISCLAIMER OF LIABILITY The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This SDS was prepared and is to be used only for this product. If the product is used as a component in another product, this SDS information may not be applicable.